Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 5/20 | 0.53 |
| ▸ | ASH1L | Q9NR48 | 1/20 | 0.43 |
| ▸ | BRD2 | P25440 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 8/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 8/20 | 0.39 |
| ▸ | CLK4 | Q9HAZ1 | 7/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 5/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | USP2 | O75604 | 5/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17632626 | 0.83 | BRD4 (0.56) | BRD4BRD2CYP1A2CYP3A4CLK4 | |
| SCHEMBL30248426 | 0.79 | BRD4 (0.54) | BRD4BRD2CYP3A4HSD17B10ALDH1A1 | |
| SCHEMBL34471204 | 0.74 | ASH1L (0.43) | BRD4ASH1LCYP1A2CYP3A4HSD17B10 | |
| SCHEMBL28490776 | 0.74 | BRD4 (0.58) | BRD4CYP1A2CYP3A4HSD17B10CYP2C19 | |
| SCHEMBL2176153 | 0.72 | BRD4 (0.44) | BRD4BRD2CYP1A2CYP3A4CLK4 | |
| SCHEMBL17632247 | 0.72 | BRD4 (0.64) | BRD4CYP1A2CYP3A4HSD17B10CYP2C19 | |
| SCHEMBL14266208 | 0.71 | BRD4 (0.42) | BRD4BRD2CYP1A2CYP3A4CLK4 | |
| SCHEMBL30312094 | 0.71 | ASH1L (0.47) | ASH1LALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL29013237 | 0.71 | ASH1L (0.47) | ASH1LALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL289210 | 0.70 | SMN1; SMN2 (0.56) | ASH1LCYP1A2CYP3A4HSD17B10CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4547247-A2 | DEUBIQUITINASE INHIBITORS AND METHODS OF USE THEREOF | Dana-Farber Cancer Institute, Inc. (US) | 2025-05-07 | — | — | EP | disclosed |
| WO-2024006956-A9 | DEUBIQUITINASE INHIBITORS AND METHODS OF USE THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2024-04-11 | — | — | WO | disclosed |
| WO-2024006956-A2 | DEUBIQUITINASE INHIBITORS AND METHODS OF USE THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2024-01-04 | — | — | WO | disclosed |