Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHMT2 | P34897 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27140449 | 1.00 | SHMT2 (0.34) | SHMT2KDM4EMEN1MAPTRAB9A | |
| SCHEMBL30718666 | 0.92 | KDM4E (0.38) | SHMT2KDM4EMEN1MAPTRAB9A | |
| SCHEMBL27152973 | 0.92 | KDM4E (0.38) | SHMT2KDM4EMEN1MAPTRAB9A | |
| SCHEMBL27138907 | 0.81 | SHMT2 (0.35) | SHMT2 | |
| SCHEMBL30718671 | 0.81 | SHMT2 (0.32) | SHMT2 | |
| SCHEMBL27138908 | 0.81 | SHMT2 (0.35) | SHMT2 | |
| SCHEMBL27142426 | 0.81 | SHMT2 (0.32) | SHMT2 | |
| SCHEMBL31413432 | 0.81 | SHMT2 (0.32) | SHMT2 | |
| SCHEMBL30718735 | 0.81 | SHMT2 (0.35) | SHMT2 | |
| SCHEMBL27142425 | 0.81 | SHMT2 (0.32) | SHMT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4547658-A1 | WEE1 DEGRADING COMPOUNDS AND USES THEREOF | Bristol-Myers Squibb Company (US) | 2025-05-07 | — | — | EP | disclosed |
| CN-119325469-A | WEE1 degrading compounds and uses thereof | 百时美施贵宝公司 | 2025-01-17 | — | — | CN | disclosed |
| WO-2024006881-A1 | WEE1 DEGRADING COMPOUNDS AND USES THEREOF | BRISTOL-MYERS SQUIBB COMPANY (US) | 2024-01-04 | — | — | WO | disclosed |