⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10076693 | 0.84 | — | — | |
| SCHEMBL5084320 | 0.84 | — | — | |
| SCHEMBL22448448 | 0.84 | — | — | |
| SCHEMBL228856 | 0.77 | — | — | |
| SCHEMBL226904 | 0.77 | — | — | |
| SCHEMBL225423 | 0.77 | — | — | |
| Hydrochloric Acid SCHEMBL7140754 | 0.75 | — | — | |
| SCHEMBL27868310 | 0.74 | RIPK1 (0.39) | — | |
| SCHEMBL26622075 | 0.72 | — | — | |
| SCHEMBL15116660 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4547658-A1 | WEE1 DEGRADING COMPOUNDS AND USES THEREOF | Bristol-Myers Squibb Company (US) | 2025-05-07 | — | — | EP | disclosed |
| WO-2024006881-A1 | WEE1 DEGRADING COMPOUNDS AND USES THEREOF | BRISTOL-MYERS SQUIBB COMPANY (US) | 2024-01-04 | — | — | WO | disclosed |