Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 16/20 | 0.53 |
| ▸ | IKZF2 | Q9UKS7 | 4/20 | 0.47 |
| ▸ | IKZF1 | Q13422 | 1/20 | 0.47 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27143832 | 1.00 | CRBN (0.53) | CRBNIKZF2IKZF1CSNK1A1 | |
| SCHEMBL27143837 | 1.00 | CRBN (0.53) | CRBNIKZF2IKZF1CSNK1A1 | |
| SCHEMBL21622006 | 0.88 | CRBN (0.56) | CRBNIKZF2IKZF1 | |
| SCHEMBL24818130 | 0.84 | CRBN (0.48) | CRBNIKZF2IKZF1 | |
| SCHEMBL24816831 | 0.84 | CRBN (0.48) | CRBNIKZF2IKZF1 | |
| SCHEMBL24745083 | 0.82 | CRBN (0.63) | CRBNIKZF2IKZF1CSNK1A1 | |
| SCHEMBL30270874 | 0.82 | CRBN (0.63) | CRBNIKZF2IKZF1CSNK1A1 | |
| SCHEMBL23350211 | 0.82 | CRBN (0.63) | CRBNIKZF2CSNK1A1 | |
| SCHEMBL20231670 | 0.82 | CRBN (0.63) | CRBNIKZF2CSNK1A1 | |
| SCHEMBL30744225 | 0.82 | CRBN (0.63) | CRBNIKZF2CSNK1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4547658-A1 | WEE1 DEGRADING COMPOUNDS AND USES THEREOF | Bristol-Myers Squibb Company (US) | 2025-05-07 | — | — | EP | disclosed |
| CN-119325469-A | WEE1 degrading compounds and uses thereof | 百时美施贵宝公司 | 2025-01-17 | — | — | CN | disclosed |
| WO-2024006881-A1 | WEE1 DEGRADING COMPOUNDS AND USES THEREOF | BRISTOL-MYERS SQUIBB COMPANY (US) | 2024-01-04 | — | — | WO | disclosed |