Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 6/20 | 0.43 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.40 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.38 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | ALPL | P05186 | 2/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.35 |
| ▸ | PI4KA | P42356 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27140044 | 1.00 | PDE10A (0.43) | PDE10AMALT1PDGFRBPDGFRATSHR | |
| SCHEMBL12850737 | 0.85 | MALT1 (0.38) | PDE10AMALT1PDGFRBPDGFRAMEN1 | |
| SCHEMBL8108097 | 0.82 | PDE10A (0.60) | PDE10APDGFRBPDGFRACYP11B1CYP11B2 | |
| SCHEMBL18562139 | 0.81 | CYP1A2 (0.40) | PDE10AMALT1TSHRRAB9AMEN1 | |
| SCHEMBL8813587 | 0.81 | CYP11B1 (0.55) | PDE10APDGFRBPDGFRARAB9AMEN1 | |
| SCHEMBL8099185 | 0.81 | PDE10A (0.43) | PDE10APDGFRBPDGFRACYP11B1CYP11B2 | |
| SCHEMBL3150525 | 0.78 | CYP1A2 (0.52) | PDE10APDGFRBPDGFRAKMT2AHTT | |
| SCHEMBL2621781 | 0.78 | BACE1 (0.38) | PDE10AMALT1RAB9AMEN1LMNA | |
| SCHEMBL2621783 | 0.77 | HTT (0.39) | MALT1PDGFRBPDGFRALMNAHTT | |
| SCHEMBL30718868 | 0.77 | ALDH1A1 (0.43) | PDE10APDGFRBPDGFRATSHRRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4547658-A1 | WEE1 DEGRADING COMPOUNDS AND USES THEREOF | Bristol-Myers Squibb Company (US) | 2025-05-07 | — | — | EP | disclosed |
| CN-119325469-A | WEE1 degrading compounds and uses thereof | 百时美施贵宝公司 | 2025-01-17 | — | — | CN | disclosed |
| WO-2024006881-A1 | WEE1 DEGRADING COMPOUNDS AND USES THEREOF | BRISTOL-MYERS SQUIBB COMPANY (US) | 2024-01-04 | — | — | WO | disclosed |