Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 11/20 | 0.49 |
| ▸ | CCND1 | P24385 | 11/20 | 0.49 |
| ▸ | CCND2 | P30279 | 11/20 | 0.49 |
| ▸ | CCND3 | P30281 | 11/20 | 0.49 |
| ▸ | CCNB2 | O95067 | 2/20 | 0.41 |
| ▸ | CCNE2 | O96020 | 2/20 | 0.41 |
| ▸ | CDK1 | P06493 | 2/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.41 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.41 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.41 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.41 |
| ▸ | FGFR4 | P22455 | 2/20 | 0.41 |
| ▸ | FGFR3 | P22607 | 2/20 | 0.41 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.41 |
| ▸ | CDK2 | P24941 | 2/20 | 0.41 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.41 |
| ▸ | CCNB3 | Q8WWL7 | 2/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2632960 | 0.83 | CDK4 (0.62) | CDK4CCND1CCND2CCND3CCNB2 | |
| SCHEMBL23141673 | 0.79 | CDK4 (0.46) | CDK4CCND1CCND2CCND3CCNB2 | |
| SCHEMBL29830311 | 0.78 | CDK4 (0.44) | CDK4CCND1CCND2CCND3CCNB2 | |
| SCHEMBL5264427 | 0.74 | CDK4 (0.54) | CDK4CCND1CCND2CCND3CCNB2 | |
| SCHEMBL8363720 | 0.74 | CTSK (0.46) | FGFR1FGFR2FGFR4FGFR3SRC | |
| SCHEMBL8363719 | 0.73 | CTSK (0.46) | — | |
| Hydrochloric Acid SCHEMBL29862011 | 0.73 | CDK4 (0.52) | CDK4CCND1CCND2CCND3CCNB2 | |
| SCHEMBL29830700 | 0.73 | CDK4 (0.58) | CDK4CCND1CCND2CCND3CCNB2 | |
| SCHEMBL23142020 | 0.73 | CDK4 (0.58) | CDK4CCND1CCND2CCND3CCNB2 | |
| SCHEMBL23141789 | 0.72 | CDK4 (0.57) | CDK4CCND1CCND2CCND3CCNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112469719-B | Heterocondensed pyridone compounds and their use as IDH inhibitors | 内尔维亚诺医疗科学公司 | 2024-01-23 | — | — | CN | disclosed |