Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | NUDT1 | P36639 | 3/20 | 0.44 |
| ▸ | MAPK8 | P45983 | 4/20 | 0.41 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.41 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.41 |
| ▸ | STK17B | O94768 | 2/20 | 0.36 |
| ▸ | STK17A | Q9UEE5 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.34 |
| ▸ | CTSS | P25774 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
| ▸ | CDK1 | P06493 | 2/20 | 0.34 |
| ▸ | CDK2 | P24941 | 2/20 | 0.34 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.34 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | BCR | P11274 | 1/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4134213 | 1.00 | MEN1 (0.46) | MEN1KMT2ANUDT1MAPK8MAPK9 | |
| SCHEMBL1938007 | 0.83 | STK17A (0.50) | MEN1KMT2ANUDT1MAPK8STK17B | |
| SCHEMBL13897499 | 0.81 | MEN1 (0.52) | MEN1KMT2ASTK17BSTK17AALDH1A1 | |
| SCHEMBL13649070 | 0.81 | KMT2A (0.41) | MEN1KMT2ASTK17BSTK17AALDH1A1 | |
| SCHEMBL4137651 | 0.80 | NUDT1 (0.51) | MEN1KMT2ANUDT1MAPK8MAPK9 | |
| SCHEMBL5436631 | 0.79 | NUDT1 (0.43) | MEN1KMT2ANUDT1MAPK8STK17B | |
| SCHEMBL13649041 | 0.78 | KMT2A (0.39) | MEN1KMT2ASTK17BSTK17AALDH1A1 | |
| SCHEMBL3447092 | 0.78 | KMT2A (0.50) | MEN1KMT2ASTK17BSTK17AALDH1A1 | |
| SCHEMBL5786509 | 0.78 | NUDT1 (0.45) | MEN1KMT2ANUDT1MAPK8MAPK9 | |
| SCHEMBL5789412 | 0.78 | NUDT1 (0.42) | MEN1KMT2ANUDT1MAPK8MAPK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112469719-B | Heterocondensed pyridone compounds and their use as IDH inhibitors | 内尔维亚诺医疗科学公司 | 2024-01-23 | — | — | CN | disclosed |