SCHEMBL30719652

SCHEMBL30719652

COc1ccc(-c2n[nH]c(=O)c3ccccc23)cc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.67
NPSR1 Q6W5P4 1/20 0.67
PDE4A P27815 1/20 0.67
PDE4B Q07343 1/20 0.67
PDE4C Q08493 1/20 0.67
PDE4D Q08499 1/20 0.67
MAPK1 P28482 1/20 0.65
ROCK1 Q13464 7/20 0.59
ROCK2 O75116 3/20 0.58
KDM4E B2RXH2 3/20 0.57
ALDH1A1 P00352 2/20 0.57
NPC1 O15118 1/20 0.57
NCOA1 Q15788 1/20 0.57
NCOA3 Q9Y6Q9 1/20 0.57
GAA P10253 2/20 0.57
MAPT P10636 2/20 0.57
CDK4 P11802 2/20 0.56
CCND1 P24385 2/20 0.56
CCNE2 O96020 1/20 0.56
CCNE1 P24864 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL710318 1.00 ATM (0.67) ATMNPSR1PDE4APDE4BPDE4C
SCHEMBL1934226 0.86 PDE4A (0.52) ATMNPSR1PDE4APDE4BPDE4C
SCHEMBL4124300 0.86 ENPP1 (0.66) ATMNPSR1PDE4APDE4BPDE4C
SCHEMBL4841775 0.84 GSK3A (0.62) ATMNPSR1PDE4APDE4BPDE4C
SCHEMBL4843618 0.83 GSK3A (0.65) ATMNPSR1PDE4APDE4BPDE4C
SCHEMBL6591973 0.83 GSK3A (0.65) ATMNPSR1PDE4APDE4BPDE4C
SCHEMBL2887372 0.83 KDM4E (0.54) ATMNPSR1PDE4APDE4BPDE4C
SCHEMBL2885503 0.82 CCNE2 (0.56) ATMNPSR1PDE4APDE4BPDE4C
SCHEMBL4837386 0.82 ENPP1 (0.56) PDE4APDE4BPDE4CPDE4DMAPK1
SCHEMBL4837888 0.82 GSK3A (0.53) PDE4APDE4BPDE4CPDE4DMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118580771-B Preparation method of light automobile chassis adhesive with good sound insulation effect 广州赫厉狮森汽车用品有限公司 2024-10-01 CN claimed
CN-118580771-A Preparation method of light automobile chassis adhesive with good sound insulation effect 广州赫厉狮森汽车用品有限公司 2024-09-03 CN claimed
CN-118496166-A Preparation method of phthalazinone compound 五邑大学 2024-08-16 CN claimed
CN-118580771-B Preparation method of light automobile chassis adhesive with good sound insulation effect 广州赫厉狮森汽车用品有限公司 2024-10-01 CN disclosed
CN-118580771-A Preparation method of light automobile chassis adhesive with good sound insulation effect 广州赫厉狮森汽车用品有限公司 2024-09-03 CN disclosed
CN-118496166-A Preparation method of phthalazinone compound 五邑大学 2024-08-16 CN disclosed
CN-117586108-A TOLL-like receptor 8 (TLR 8) specific antagonists, methods of making and uses thereof 科罗拉多州立大学董事会法人团体 2024-02-23 CN disclosed
CN-117586191-A TOLL-like receptor 8 (TLR 8) specific antagonists, methods of making and uses thereof 科罗拉多州立大学董事会法人团体 2024-02-23 CN disclosed
CN-111542515-B TOLL-like receptor 8 (TLR 8) specific antagonists, methods of making and uses thereof 科罗拉多州立大学董事会法人团体 2023-12-05 CN disclosed