Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3A | P49840 | 2/20 | 0.65 |
| ▸ | GSK3B | P49841 | 2/20 | 0.65 |
| ▸ | ATM | Q13315 | 1/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | ROCK1 | Q13464 | 4/20 | 0.55 |
| ▸ | PDE4A | P27815 | 1/20 | 0.55 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.55 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.55 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.55 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.54 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | CASR | P41180 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | TTK | P33981 | 2/20 | 0.48 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4843618 | 0.94 | GSK3A (0.65) | GSK3AGSK3BATMNPSR1ALDH1A1 | |
| SCHEMBL4841775 | 0.92 | GSK3A (0.62) | GSK3AGSK3BATMNPSR1ALDH1A1 | |
| SCHEMBL4124300 | 0.85 | ENPP1 (0.66) | GSK3AGSK3BATMNPSR1ALDH1A1 | |
| SCHEMBL4838570 | 0.84 | ENPP1 (0.56) | GSK3AGSK3BATMNPSR1ALDH1A1 | |
| SCHEMBL710318 | 0.83 | ATM (0.67) | GSK3AGSK3BATMNPSR1ALDH1A1 | |
| SCHEMBL30719652 | 0.83 | ATM (0.67) | GSK3AGSK3BATMNPSR1ALDH1A1 | |
| SCHEMBL24000722 | 0.82 | ENPP1 (0.64) | GSK3AGSK3BROCK1PDE4APDE4B | |
| Hydrochloric Acid SCHEMBL30088895 | 0.81 | ENPP1 (0.62) | GSK3AGSK3BROCK1PDE4APDE4B | |
| SCHEMBL4844032 | 0.81 | ENPP1 (0.62) | GSK3AGSK3BATMNPSR1ALDH1A1 | |
| SCHEMBL4837888 | 0.81 | GSK3A (0.53) | GSK3AGSK3BALDH1A1KDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118496166-A | Preparation method of phthalazinone compound | 五邑大学 | 2024-08-16 | — | — | CN | disclosed |
| EP-1097142-B1 | PHTHALAZINE DERIVATIVES PHOSPHODIESTERASE 4 INHIBITORS | ZAMBON SPA (IT) | 2004-10-13 | — | — | EP | disclosed |
| US-6492360-B1 | Phthalazine derivatives phosphodiesterase 4 inhibitors | ZAMBON GROUP S.P.A. (IT) | 2002-12-10 | — | — | US | disclosed |
| US-6329370-B1 | CARDIOVASCULAR DISORDERS AND TUMOR NECROSIS FACTOR (HEREINAFTER TNF.SUB..ALPHA.), A CYTOKINE WITH PRO-INFLAMMATORY ACTIVITY | ZAMBON GROUP S.P.A. (IT) | 2001-12-11 | — | — | US | disclosed |
| EP-1097142-A1 | PHTHALAZINE DERIVATIVES PHOSPHODIESTERASE 4 INHIBITORS | ZAMBON GROUP S.p.A. (IT) | 2001-05-09 | — | — | EP | disclosed |
| WO-2000005218-A1 | PHTHALAZINE DERIVATIVES PHOSPHODIESTERASE 4 INHIBITORS | ZAMBON GROUP S.P.A. (IT) | 2000-02-03 | — | — | WO | disclosed |