SCHEMBL30719871

CC[C@H](C)[C@H](NC(=O)[C@H](CCC(N)=O)NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(=O)O)NC(=O)[C@@H](N)CCCCN)C(=O)O

nearest known ligand 0.53

Predicted protein targets (top 5)

	gene	UniProt	supporting neighbours	confidence
▸	BACE1	P56817	1/20	0.53

▸	F2	P00734	2/20	0.52

▸	OPRL1	P41146	1/20	0.49

▸	PTPN1	P18031	1/20	0.48

▸	GLP1R	P43220	2/20	0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL30719903	0.95	BACE1 (0.56)	BACE1F2OPRL1PTPN1GLP1R
SCHEMBL30719881	0.91	F2 (0.55)	BACE1F2OPRL1PTPN1GLP1R
SCHEMBL10694201	0.88	BACE1 (0.60)	BACE1GLP1R
SCHEMBL30054333	0.86	F2 (0.57)	BACE1F2
SCHEMBL29702470	0.85	TFPI (0.54)	F2GLP1R
SCHEMBL31688322	0.84	VIPR2 (0.57)	BACE1F2GLP1R
SCHEMBL31603940	0.84	BACE1 (0.66)	BACE1GLP1R
SCHEMBL30708073	0.84	F2 (0.58)	BACE1F2GLP1R
SCHEMBL29373116	0.84	BACE1 (0.61)	BACE1F2
SCHEMBL29702389	0.83	TFPI (0.54)	F2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2024003873-A1	SINGLE VARIABLE DOMAIN ANTIBODIES AGAINST TUMOR NECROSIS FACTOR-ALPHA	INTREXON ACTOBIOTICS NV D/B/A PRECIGEN ACTOBIO (BE)	2024-01-04	—	—	WO	claimed
WO-2024003873-A1	SINGLE VARIABLE DOMAIN ANTIBODIES AGAINST TUMOR NECROSIS FACTOR-ALPHA	INTREXON ACTOBIOTICS NV D/B/A PRECIGEN ACTOBIO (BE)	2024-01-04	—	—	WO	disclosed