SCHEMBL30719903

CC[C@H](C)[C@H](NC(=O)[C@H](CCC(N)=O)NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(=O)O)NC(=O)[C@@H](N)CCCCN)C(=O)N[C@@H](CCCCN)C(=O)O

nearest known ligand 0.57

Predicted protein targets (top 8)

	gene	UniProt	supporting neighbours	confidence
▸	BACE1	P56817	2/20	0.56

▸	F2	P00734	2/20	0.56

▸	PTPN1	P18031	1/20	0.51

▸	GLP1R	P43220	2/20	0.49

▸	OPRD1	P41143	1/20	0.49

▸	OPRL1	P41146	1/20	0.49

▸	VIPR1	P32241	1/20	0.48

▸	VIPR2	P41587	1/20	0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL30719881	0.96	F2 (0.55)	BACE1F2PTPN1GLP1ROPRD1
SCHEMBL30719871	0.95	BACE1 (0.53)	BACE1F2PTPN1GLP1ROPRL1
SCHEMBL29373116	0.90	BACE1 (0.61)	BACE1F2
SCHEMBL31603940	0.89	BACE1 (0.66)	BACE1GLP1RVIPR1VIPR2
SCHEMBL30277899	0.88	BACE1 (0.62)	BACE1VIPR1VIPR2
SCHEMBL30906473	0.88	OPRL1 (0.52)	BACE1F2GLP1ROPRL1VIPR2
SCHEMBL10694201	0.88	BACE1 (0.60)	BACE1GLP1RVIPR1VIPR2
SCHEMBL30788717	0.88	F2 (0.58)	BACE1F2
SCHEMBL31688322	0.87	VIPR2 (0.57)	BACE1F2GLP1RVIPR1VIPR2
SCHEMBL29410012	0.87	BACE1 (0.58)	BACE1GLP1ROPRL1VIPR1VIPR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2024003873-A1	SINGLE VARIABLE DOMAIN ANTIBODIES AGAINST TUMOR NECROSIS FACTOR-ALPHA	INTREXON ACTOBIOTICS NV D/B/A PRECIGEN ACTOBIO (BE)	2024-01-04	—	—	WO	disclosed