Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 4/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.35 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.35 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | RECQL | P46063 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5222990 | 0.89 | ADORA3 (0.38) | ADORA3ADORA2AABCB1ALDH1A1MEN1 | |
| SCHEMBL5223742 | 0.87 | BRD4 (0.37) | ADORA3ADORA2AABCB1ADORA1AAK1 | |
| SCHEMBL5223751 | 0.87 | BRD4 (0.37) | ADORA3ADORA2AABCB1ADORA1AAK1 | |
| SCHEMBL29153689 | 0.83 | POLB (0.43) | POLBL3MBTL1GAAALDH1A1LMNA | |
| SCHEMBL29153687 | 0.83 | POLB (0.43) | POLBL3MBTL1GAAALDH1A1LMNA | |
| SCHEMBL5217792 | 0.82 | ABCB1 (0.35) | ADORA3ADORA2AABCB1LMNAADORA1 | |
| SCHEMBL5217784 | 0.82 | ABCB1 (0.35) | ADORA3ADORA2AABCB1LMNAADORA1 | |
| SCHEMBL5759888 | 0.82 | PCSK9 (0.40) | ADORA3ADORA2AL3MBTL1ABCB1ALDH1A1 | |
| SCHEMBL5759892 | 0.82 | PCSK9 (0.40) | ADORA3ADORA2AL3MBTL1ABCB1ALDH1A1 | |
| SCHEMBL5218644 | 0.82 | BRD4 (0.37) | ADORA3ADORA2AABCB1ADORA1AAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117396485-A | PARP7 inhibitors | 轩竹生物科技股份有限公司 | 2024-01-12 | — | — | CN | disclosed |