SCHEMBL30720904

SCHEMBL30720904

Cc1c(Br)ccc2c1CN(N1C(=O)CCCC1=O)C2=O

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PDE3B Q13370 1/20 0.32
PDE3A Q14432 1/20 0.32
SRD5A1 P18405 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30720927 0.83
SCHEMBL30912159 0.83 HTR2A (0.33)
SCHEMBL30720916 0.82 ALDH1A1 (0.33)
SCHEMBL19438879 0.79 PARP10 (0.40)
SCHEMBL29842102 0.79 PARP10 (0.40)
SCHEMBL30720895 0.74 NOTUM (0.30)
SCHEMBL23787516 0.71 BRD4 (0.44)
SCHEMBL29188527 0.71 SRD5A1 (0.43) SRD5A1
SCHEMBL30080874 0.71 CRBN (0.45)
SCHEMBL30697519 0.71 KMT2A (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117321046-A Indazole-based compounds and related methods of use 阿维纳斯企业公司 2023-12-29 CN disclosed