Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | HPGD | P15428 | 2/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.62 |
| ▸ | NPC1 | O15118 | 1/20 | 0.62 |
| ▸ | RAB9A | P51151 | 1/20 | 0.62 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.53 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.53 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.53 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.49 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.48 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.48 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.48 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.48 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20116563 | 1.00 | KDM4E (0.62) | KDM4EALDH1A1HPGDHSD17B10NPC1 | |
| SCHEMBL13417168 | 0.88 | USP30 (0.53) | KDM4EALDH1A1HPGDHSD17B10NPC1 | |
| SCHEMBL10040509 | 0.85 | USP30 (0.53) | USP30GPR119TBK1SMN1; SMN2HTT | |
| SCHEMBL14327894 | 0.84 | USP30 (0.51) | KDM4EALDH1A1HPGDHSD17B10NPC1 | |
| SCHEMBL408322 | 0.83 | USP30 (0.57) | KDM4EUSP30GPR119TBK1SMN1; SMN2 | |
| SCHEMBL20676675 | 0.83 | USP30 (0.53) | KDM4EALDH1A1HPGDHSD17B10NPC1 | |
| SCHEMBL26187318 | 0.82 | USP30 (0.55) | KDM4EUSP30GPR119TBK1SMN1; SMN2 | |
| SCHEMBL1654779 | 0.82 | USP30 (0.51) | KDM4EUSP30GPR119TBK1SMN1; SMN2 | |
| SCHEMBL20676325 | 0.81 | USP30 (0.49) | KDM4EALDH1A1HPGDHSD17B10USP30 | |
| SCHEMBL20116416 | 0.81 | USP30 (0.51) | KDM4EUSP30GPR119TBK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11873298-B2 | Compounds and uses thereof | JANSSEN PHARMACEUTICA NV (BE) | 2024-01-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11873298-B2 | Compounds and uses thereof | NLN, ACHE, CLN6 | KDM4E 2853/4885ALDH1A1 656/4885HPGD 565/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.