Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 10/20 | 0.49 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.47 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.45 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.40 |
| ▸ | MTOR | P42345 | 1/20 | 0.40 |
| ▸ | KIT | P10721 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22172329 | 1.00 | MAP4K4 (0.49) | MAP4K4TGFBR1ADORA2BPDE10ALMNA | |
| SCHEMBL30721861 | 0.92 | MAP4K4 (0.50) | MAP4K4TGFBR1ADORA2BLMNA | |
| SCHEMBL22172384 | 0.92 | MAP4K4 (0.50) | MAP4K4TGFBR1ADORA2BLMNA | |
| SCHEMBL22172397 | 0.89 | MAP4K4 (0.54) | MAP4K4TGFBR1ADORA2BLMNACLK4 | |
| SCHEMBL23988236 | 0.85 | MAP4K4 (0.57) | MAP4K4TGFBR1LMNACYP1A2CYP3A4 | |
| SCHEMBL21621288 | 0.84 | ADORA1 (0.55) | MAP4K4TGFBR1PIK3CDPIK3CAMTOR | |
| SCHEMBL30738227 | 0.84 | MAP4K4 (0.51) | MAP4K4TGFBR1LMNACYP1A2CYP3A4 | |
| SCHEMBL22180298 | 0.84 | MAP4K4 (0.51) | MAP4K4TGFBR1LMNACYP1A2CYP3A4 | |
| SCHEMBL29947057 | 0.84 | ADORA1 (0.55) | MAP4K4TGFBR1PIK3CDPIK3CAMTOR | |
| SCHEMBL22172387 | 0.83 | ADORA2B (0.51) | MAP4K4TGFBR1ADORA2BPDE10AUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113166119-B | Substituted aryl compound and preparation method and application thereof | 四川科伦博泰生物医药股份有限公司 | 2024-01-05 | — | — | CN | disclosed |
| CN-113166109-B | Aminopyridine compound and preparation method and application thereof | 四川科伦博泰生物医药股份有限公司 | 2024-01-02 | — | — | CN | disclosed |