Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 9/20 | 0.45 |
| ▸ | PI4K2A | Q9BTU6 | 7/20 | 0.43 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.42 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.41 |
| ▸ | DHODH | Q02127 | 2/20 | 0.39 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22172331 | 1.00 | MAP4K4 (0.45) | MAP4K4PI4K2ATGFBR1PI4KBDHODH | |
| SCHEMBL30721854 | 0.93 | MAP4K4 (0.46) | MAP4K4PI4K2ATGFBR1PI4KB | |
| SCHEMBL22172380 | 0.93 | MAP4K4 (0.46) | MAP4K4PI4K2ATGFBR1PI4KB | |
| SCHEMBL22172332 | 0.92 | MAP4K4 (0.45) | MAP4K4TGFBR1DHODH | |
| SCHEMBL30721822 | 0.92 | MAP4K4 (0.45) | MAP4K4TGFBR1DHODH | |
| SCHEMBL22172381 | 0.91 | MAP4K4 (0.51) | MAP4K4PI4K2ATGFBR1PI4KBDHODH | |
| SCHEMBL30721843 | 0.91 | MAP4K4 (0.51) | MAP4K4PI4K2ATGFBR1PI4KBDHODH | |
| SCHEMBL24211167 | 0.90 | TGFBR1 (0.43) | MAP4K4PI4K2ATGFBR1PI4KBDHODH | |
| SCHEMBL22163837 | 0.89 | MAP4K4 (0.44) | MAP4K4TGFBR1 | |
| SCHEMBL22172330 | 0.89 | MAP4K4 (0.43) | MAP4K4TGFBR1DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113166109-B | Aminopyridine compound and preparation method and application thereof | 四川科伦博泰生物医药股份有限公司 | 2024-01-02 | — | — | CN | disclosed |