SCHEMBL30722115

SCHEMBL30722115

CN1CCC(NC(=O)c2ccc3c(c2)sc2nc(-c4ccc(C5CCN(C(=O)OC(C)(C)C)C5)cc4F)cn23)CC1

nearest known ligand 0.52

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 7/20 0.52
▸ ALDH1A1 P00352 3/20 0.52
▸ KDM4E B2RXH2 2/20 0.52
▸ NPC1 O15118 1/20 0.52
▸ ATM Q13315 1/20 0.52
▸ LMNA P02545 4/20 0.51
▸ TP53 P04637 3/20 0.51
▸ HPGD P15428 2/20 0.50
▸ THRB P10828 2/20 0.49
▸ ALOX15 P16050 1/20 0.49
▸ HSD17B10 Q99714 1/20 0.49
▸ POLB P06746 1/20 0.48
▸ RXFP1 Q9HBX9 2/20 0.47
▸ LCK P06239 1/20 0.41
▸ JAK3 P52333 1/20 0.41
▸ BTK Q06187 1/20 0.41
▸ SLC2A1 P11166 1/20 0.41
▸ BRD4 O60885 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26987410 1.00 MAPT (0.52) MAPTALDH1A1KDM4ENPC1ATM
SCHEMBL26987795 0.91 MAPT (0.48) MAPTALDH1A1KDM4ENPC1ATM
SCHEMBL30722198 0.91 MAPT (0.48) MAPTALDH1A1KDM4ENPC1ATM
SCHEMBL31290622 0.91 MAPT (0.48) MAPTALDH1A1KDM4ENPC1ATM
SCHEMBL26987414 0.90 MAPT (0.46) MAPTALDH1A1KDM4ENPC1ATM
SCHEMBL31290657 0.90 MAPT (0.46) MAPTALDH1A1KDM4ENPC1ATM
SCHEMBL30722122 0.90 MAPT (0.46) MAPTALDH1A1KDM4ENPC1ATM
SCHEMBL31327697 0.89 PDE4B (0.42) MAPTALDH1A1KDM4ENPC1ATM
SCHEMBL30727242 0.89 PDE4B (0.42) MAPTALDH1A1KDM4ENPC1ATM
SCHEMBL26985371 0.89 PDE4B (0.42) MAPTALDH1A1KDM4ENPC1ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4547672-A1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER Anima Biotech Inc. (US) 2025-05-07 — — EP disclosed
WO-2024010762-A1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER ANIMA BIOTECH INC. (US) 2024-01-11 — — WO disclosed
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