SCHEMBL30722143

SCHEMBL30722143

CN1CCC(NC(=O)c2ccc3c(c2)sc2nc(-c4ccc(C5COCCN5C(=O)OC(C)(C)C)cc4F)cn23)CC1

nearest known ligand 0.47

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 8/20 0.47
▸ LMNA P02545 4/20 0.47
▸ TP53 P04637 4/20 0.47
▸ ALDH1A1 P00352 3/20 0.46
▸ KDM4E B2RXH2 2/20 0.46
▸ NPC1 O15118 1/20 0.46
▸ ATM Q13315 1/20 0.46
▸ THRB P10828 2/20 0.46
▸ HPGD P15428 2/20 0.45
▸ POLB P06746 1/20 0.44
▸ ALOX15 P16050 1/20 0.44
▸ HSD17B10 Q99714 1/20 0.44
▸ RXFP1 Q9HBX9 2/20 0.43
▸ SLC2A1 P11166 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26987387 1.00 MAPT (0.47) MAPTLMNATP53ALDH1A1KDM4E
SCHEMBL31290647 1.00 MAPT (0.47) MAPTLMNATP53ALDH1A1KDM4E
SCHEMBL31290640 0.95 MAPT (0.48) MAPTLMNATP53ALDH1A1KDM4E
SCHEMBL30722105 0.95 MAPT (0.48) MAPTLMNATP53ALDH1A1KDM4E
SCHEMBL26987614 0.95 MAPT (0.48) MAPTLMNATP53ALDH1A1KDM4E
SCHEMBL31290623 0.92 MAPT (0.52) MAPTLMNATP53ALDH1A1KDM4E
SCHEMBL31290650 0.92 MAPT (0.52) MAPTLMNATP53ALDH1A1KDM4E
SCHEMBL30722124 0.92 MAPT (0.52) MAPTLMNATP53ALDH1A1KDM4E
SCHEMBL30722135 0.92 MAPT (0.52) MAPTLMNATP53ALDH1A1KDM4E
SCHEMBL31290610 0.92 MAPT (0.52) MAPTLMNATP53ALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4547672-A1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER Anima Biotech Inc. (US) 2025-05-07 — — EP disclosed
WO-2024010762-A1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER ANIMA BIOTECH INC. (US) 2024-01-11 — — WO disclosed
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