SCHEMBL31290640

SCHEMBL31290640

CC(C)(C)OC(=O)N1CCOCC1c1ccc(-c2cn3c(n2)sc2cc(C(=O)NC4CCOCC4)ccc23)c(F)c1

nearest known ligand 0.48

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 7/20 0.48
▸ LMNA P02545 4/20 0.48
▸ TP53 P04637 3/20 0.48
▸ THRB P10828 2/20 0.47
▸ ALDH1A1 P00352 3/20 0.46
▸ KDM4E B2RXH2 2/20 0.46
▸ NPC1 O15118 1/20 0.46
▸ ATM Q13315 1/20 0.46
▸ POLB P06746 1/20 0.45
▸ HPGD P15428 2/20 0.44
▸ RXFP1 Q9HBX9 2/20 0.44
▸ ALOX15 P16050 1/20 0.43
▸ HSD17B10 Q99714 1/20 0.43
▸ SLC2A1 P11166 1/20 0.38
▸ USP30 Q70CQ3 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30722105 1.00 MAPT (0.48) MAPTLMNATP53THRBALDH1A1
SCHEMBL26987614 1.00 MAPT (0.48) MAPTLMNATP53THRBALDH1A1
SCHEMBL31290647 0.95 MAPT (0.47) MAPTLMNATP53THRBALDH1A1
SCHEMBL30722143 0.95 MAPT (0.47) MAPTLMNATP53THRBALDH1A1
SCHEMBL26987387 0.95 MAPT (0.47) MAPTLMNATP53THRBALDH1A1
SCHEMBL26987370 0.93 MAPT (0.51) MAPTLMNATP53THRBALDH1A1
SCHEMBL30722043 0.93 MAPT (0.51) MAPTLMNATP53THRBALDH1A1
SCHEMBL31290637 0.90 MAPT (0.48) MAPTLMNATP53THRBALDH1A1
SCHEMBL30722076 0.90 MAPT (0.48) MAPTLMNATP53THRBALDH1A1
SCHEMBL26987537 0.90 MAPT (0.48) MAPTLMNATP53THRBALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119233976-A Modulators of c-MYC mRNA translation and their use in the treatment of cancer 艾尼莫生物科技公司 2024-12-31 — — CN disclosed
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