Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.56 |
| ▸ | MAPT | P10636 | 7/20 | 0.56 |
| ▸ | RAB9A | P51151 | 6/20 | 0.56 |
| ▸ | GAA | P10253 | 4/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | CLK1 | P49759 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.55 |
| ▸ | MEN1 | O00255 | 6/20 | 0.55 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.55 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.55 |
| ▸ | RELA | Q04206 | 3/20 | 0.55 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.55 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | ALOX5 | P09917 | 5/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30723291 | 0.80 | MAPT (0.54) | TRPV4MAPTRAB9ANPC1ALDH1A1 | |
| SCHEMBL1822611 | 0.76 | SMN1; SMN2 (0.84) | SMN1; SMN2MAPTRAB9AGAANPC1 | |
| SCHEMBL7554523 | 0.76 | ALOX5 (0.84) | SMN1; SMN2MAPTRAB9AGAANPC1 | |
| SCHEMBL29152957 | 0.76 | MEN1 (0.76) | SMN1; SMN2MAPTRAB9AGAANPC1 | |
| SCHEMBL29152952 | 0.75 | SMN1; SMN2 (0.57) | TRPV4SMN1; SMN2MAPTRAB9AGAA | |
| SCHEMBL29152955 | 0.75 | SMN1; SMN2 (0.57) | TRPV4SMN1; SMN2MAPTRAB9AGAA | |
| SCHEMBL1347261 | 0.75 | NPC1 (0.48) | SMN1; SMN2MAPTRAB9AGAANPC1 | |
| Bromide SCHEMBL7670429 | 0.74 | ALOX5 (0.82) | SMN1; SMN2MAPTRAB9AGAANPC1 | |
| SCHEMBL29152958 | 0.73 | CSNK2A1 (0.71) | TRPV4SMN1; SMN2MAPTRAB9AGAA | |
| SCHEMBL14880942 | 0.73 | ALOX5 (0.73) | SMN1; SMN2MAPTRAB9AGAANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117486872-A | Mechanical ball milling synthesis method of aminothiazole compound | 浙江工业大学 | 2024-02-02 | — | — | CN | disclosed |