Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | F11 | P03951 | 5/20 | 0.31 |
| ▸ | KLKB1 | P03952 | 5/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 3/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.31 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.31 |
| ▸ | ATR | Q13535 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30723748 | 0.84 | NPC1 (0.34) | NPC1RAB9AF11KLKB1ALDH1A1 | |
| SCHEMBL30723867 | 0.82 | NPC1 (0.33) | NPC1RAB9AF11KLKB1DGAT2 | |
| SCHEMBL30723941 | 0.81 | NPC1 (0.34) | NPC1RAB9AF11KLKB1HTR2C | |
| SCHEMBL25917540 | 0.79 | CYP4F2 (0.34) | DGAT2 | |
| SCHEMBL25918435 | 0.78 | CYP4F2 (0.37) | DGAT2 | |
| SCHEMBL30723774 | 0.75 | — | — | |
| SCHEMBL30723996 | 0.74 | — | — | |
| SCHEMBL25917542 | 0.73 | CYP4F2 (0.34) | ALDH1A1DGAT2 | |
| SCHEMBL30723776 | 0.72 | — | — | |
| SCHEMBL30723813 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024006776-A1 | ESTROGEN RECEPTOR ALPHA DEGRADERS AND MEDICAL USE THEREOF | RELAY THERAPEUTICS, INC. (US) | 2024-01-04 | — | — | WO | disclosed |