Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADA | P00813 | 12/20 | 0.74 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7452471 | 0.85 | ADA (1.00) | ADA | |
| SCHEMBL31069509 | 0.75 | HSD17B10 (0.45) | ADAADRA1DMAPK1 | |
| SCHEMBL9714567 | 0.72 | ADA (0.66) | ADA | |
| SCHEMBL10414274 | 0.72 | KDM2B (0.47) | ADAPARP1MAPK1 | |
| SCHEMBL7457279 | 0.68 | ADA (0.78) | ADA | |
| SCHEMBL7664339 | 0.67 | ADA (0.69) | ADA | |
| SCHEMBL7668671 | 0.67 | ADA (0.77) | ADA | |
| SCHEMBL7827340 | 0.66 | ADA (0.61) | ADA | |
| Fr-221647 SCHEMBL7659103 | 0.66 | ADA (1.00) | ADA | |
| Urea SCHEMBL27762549 | 0.66 | CACNA2D1 (0.52) | MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107922387-B | Heterocyclic inhibitors of ERK1 and ERK2 and their use in cancer treatment | 阿沙纳生物科学公司 | 2024-11-22 | — | — | CN | disclosed |
| CN-113200961-B | Heterocyclic inhibitors of ERK1 and ERK2 and their use in cancer treatment | 阿沙纳生物科学公司 | 2023-12-22 | — | — | CN | disclosed |