Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADA | P00813 | 13/20 | 1.00 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.43 |
| ▸ | SRC | P12931 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30724486 | 0.85 | ADA (0.74) | ADA | |
| SCHEMBL9714567 | 0.79 | ADA (0.66) | ADA | |
| Fr-221647 SCHEMBL7659103 | 0.76 | ADA (1.00) | ADA | |
| SCHEMBL7661354 | 0.76 | ADA (0.66) | ADA | |
| SCHEMBL7827340 | 0.76 | ADA (0.61) | ADAKDM4C | |
| SCHEMBL7260042 | 0.74 | ADA (0.59) | ADAKDM4C | |
| SCHEMBL6173265 | 0.74 | ADA (0.59) | ADA | |
| SCHEMBL7664339 | 0.72 | ADA (0.69) | ADA | |
| SCHEMBL7661357 | 0.70 | ADA (0.58) | ADA | |
| SCHEMBL7659109 | 0.70 | ADA (0.66) | ADA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1291979-C | Imidazole compounds and their use as adenosine deaminase inhibitors | JUJISAWA PHARAMCEUTICAL CO LTD (JP) | 2006-12-27 | — | — | CN | disclosed |
| US-6359145-B1 | ADENOSINE DEAMINASE INHIBITOR; ANTIINFLAMMATORY AGENTS; IMMUNOSUPPRESSANT | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-03-19 | — | — | US | disclosed |
| CN-1319095-A | Imidazole compounds and their use as adenosine deaminase inhibitors | JUJISAWA PHARAMCEUTICAL CO LTD (JP) | 2001-10-24 | — | — | CN | disclosed |
| WO-2001026605-A2 | IMMUNOSUPPRESSIVE COMPOSITION CONTAINING IL-2 INHIBITOR AND AN ADENOSINE DEAMINASE INHIBITOR | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-04-19 | — | — | WO | disclosed |