SCHEMBL30724712

SCHEMBL30724712

CN(CC(=O)O)C(=O)[C@@H](N)Cc1cccnc1

nearest known ligand 0.53

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 1/20 0.53
▸ NAPRT Q6XQN6 1/20 0.48
▸ KDM4E B2RXH2 1/20 0.46
▸ TBXAS1 P24557 10/20 0.44
▸ HSD17B10 Q99714 1/20 0.43
▸ FDPS P14324 1/20 0.43
▸ RIPK1 Q13546 1/20 0.43
▸ PKM P14618 1/20 0.42
▸ KMT2A Q03164 1/20 0.42
▸ CHRNB2 P17787 1/20 0.42
▸ CHRNA4 P43681 1/20 0.42
▸ CHRM1 P11229 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27428878 0.91 LMNA (0.51) LMNANAPRTKDM4ETBXAS1FDPS
SCHEMBL27389181 0.90 LMNA (0.50) LMNANAPRTKDM4ETBXAS1FDPS
SCHEMBL30918312 0.90 LMNA (0.50) LMNANAPRTKDM4ETBXAS1FDPS
SCHEMBL27232239 0.88 LMNA (0.49) LMNANAPRTKDM4ETBXAS1FDPS
SCHEMBL27228617 0.88 LMNA (0.49) LMNANAPRTKDM4ETBXAS1FDPS
SCHEMBL30901822 0.88 LMNA (0.49) LMNANAPRTKDM4ETBXAS1FDPS
SCHEMBL2498555 0.85 LMNA (0.52) LMNANAPRTKDM4ETBXAS1FDPS
SCHEMBL26343733 0.85 LMNA (0.52) LMNANAPRTKDM4ETBXAS1FDPS
SCHEMBL11357126 0.84 ALPI (0.56) PKM
Hydrochloric Acid SCHEMBL2107362 0.83 LMNA (0.51) LMNANAPRTKDM4ETBXAS1FDPS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4547337-A1 NEW PEPTIDES AS SELECTIVE IL-23 RECEPTOR ANTAGONISTS Sanofi (FR) 2025-05-07 — — EP disclosed
WO-2024003313-A9 NEW PEPTIDES AS SELECTIVE IL-23 RECEPTOR ANTAGONISTS SANOFI (FR) 2025-03-20 — — WO disclosed
WO-2024003313-A1 NEW PEPTIDES AS SELECTIVE IL-23 RECEPTOR ANTAGONISTS SANOFI (FR) 2024-01-04 — — WO disclosed
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