Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | PIM1 | P11309 | 1/20 | 0.44 |
| ▸ | SLC27A2 | O14975 | 1/20 | 0.44 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | MGAM | O43451 | 1/20 | 0.43 |
| ▸ | SI | P14410 | 1/20 | 0.43 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.43 |
| ▸ | ALPL | P05186 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29143018 | 1.00 | TP53 (0.62) | TP53LMNAPIM1SLC27A2ADAMTS5 | |
| SCHEMBL2499348 | 0.83 | IDO1 (0.47) | TP53LMNAMAPTALDH1A1KDM4E | |
| SCHEMBL29143002 | 0.83 | GAA (0.55) | TP53LMNAADAMTS5MAPTALDH1A1 | |
| SCHEMBL24281107 | 0.82 | KMT2A (0.58) | TP53LMNAALDH1A1POLBGAA | |
| SCHEMBL30725543 | 0.82 | KMT2A (0.58) | TP53LMNAALDH1A1POLBGAA | |
| SCHEMBL16197245 | 0.80 | BRD4 (0.52) | TP53LMNAPIM1SLC27A2ADAMTS5 | |
| SCHEMBL2499492 | 0.76 | BRD4 (0.57) | TP53LMNAPIM1MAPTALDH1A1 | |
| SCHEMBL13733022 | 0.74 | TP53 (0.48) | TP53LMNAPIM1SLC27A2ADAMTS5 | |
| SCHEMBL16107987 | 0.73 | BRD4 (0.75) | — | |
| SCHEMBL16197051 | 0.71 | BRD4 (0.54) | TP53LMNAPIM1ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117447393-A | Preparation method of intermediate of Rayleigh Malun | 浙江雅辰药物科技股份有限公司 | 2024-01-26 | — | — | CN | disclosed |