Sugi Predict

Sugi Predict / Compounds / SCHEMBL30725795

SCHEMBL30725795

SCHEMBL30725795

CC(C)(C)OC(=O)NC1CCN(c2cnc(-c3ccccc3)c(-c3ccccc3)n2)CC1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ CKS1B P61024 20/20 1.00
▸ SKP1 P63208 20/20 1.00
▸ SKP2 Q13309 20/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29161326 1.00 CKS1B (1.00) CKS1BSKP1SKP2
SCHEMBL30725767 0.86 CKS1B (1.00) CKS1BSKP1SKP2
SCHEMBL28933473 0.86 CKS1B (1.00) CKS1BSKP1SKP2
SCHEMBL28933440 0.85 CKS1B (1.00) CKS1BSKP1SKP2
SCHEMBL28697299 0.81 CKS1B (1.00) CKS1BSKP1SKP2
SCHEMBL30929909 0.80 CKS1B (0.74) CKS1BSKP1SKP2
SCHEMBL30725782 0.80 CKS1B (1.00) CKS1BSKP1SKP2
SCHEMBL28707164 0.80 CKS1B (1.00) CKS1BSKP1SKP2
SCHEMBL28933475 0.79 CKS1B (1.00) CKS1BSKP1SKP2
SCHEMBL649039 0.79 CKS1B (0.65) CKS1BSKP1SKP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118206499-A 2,3, 5-Trisubstituted pyrazine compound and preparation method and application thereof 郑州大学 2024-06-18 — — CN disclosed
CN-118146165-A 2,3, 5-Trisubstituted pyrazine compound and preparation method and application thereof 郑州大学 2024-06-07 — — CN disclosed
CN-113968824-B 2,3, 5-trisubstituted pyrazine compound and preparation method and application thereof 郑州大学 2024-01-19 — — CN disclosed