SCHEMBL30725957

SCHEMBL30725957

O=C(O)c1cccc(-c2cccc(C(=O)O)c2)c1

nearest known ligand 0.91

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMO O15229 2/20 0.86
RXRA P19793 2/20 0.73
RXRB P28702 2/20 0.73
CA12 O43570 1/20 0.62
CA1 P00915 1/20 0.62
CA2 P00918 1/20 0.62
CA6 P23280 1/20 0.62
CA9 Q16790 1/20 0.62
KEAP1 Q14145 1/20 0.62
LMNA P02545 1/20 0.61
GAA P10253 1/20 0.61
ERN1 O75460 1/20 0.61
CD74 P04233 1/20 0.58
MIF P14174 1/20 0.58
CYP1A2 P05177 1/20 0.58
CYP2C9 P11712 1/20 0.58
HPGD P15428 1/20 0.58
HSD17B10 Q99714 1/20 0.58
DAO P14920 1/20 0.57
TSHR P16473 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL71238 1.00 KMO (0.86) KMORXRARXRBCA12CA1
SCHEMBL29904709 1.00 KMO (0.86) KMORXRARXRBCA12CA1
SCHEMBL29276453 0.97 KMO (0.83) KMORXRARXRBCA12CA1
Fluoride SCHEMBL21332075 0.97 KMO (0.83) KMORXRARXRBCA12CA1
SCHEMBL437537 0.97 KMO (0.91) KMORXRARXRBCA12CA1
Water SCHEMBL10348973 0.97 KMO (0.83) KMORXRARXRBCA12CA1
SCHEMBL29152908 0.97 KMO (0.91) KMORXRARXRBCA12CA1
Hydrochloric Acid SCHEMBL21173951 0.97 KMO (0.83) KMORXRARXRBCA12CA1
Hydrochloric Acid SCHEMBL4350309 0.97 KMO (0.83) KMORXRARXRBCA12CA1
SCHEMBL10613691 0.97 KMO (0.83) KMORXRARXRBCA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117399071-A Chiral bifunctional catalyst UiO-67-Pro-Ru and preparation method and application thereof 东南大学 2024-01-16 CN claimed
CN-117399071-A Chiral bifunctional catalyst UiO-67-Pro-Ru and preparation method and application thereof 东南大学 2024-01-16 CN disclosed
CN-117399071-A Chiral bifunctional catalyst UiO-67-Pro-Ru and preparation method and application thereof 东南大学 2024-01-16 CN disclosed