SCHEMBL30727615

SCHEMBL30727615

O=c1[nH]cc(-n2cc3c(N4CC(F)(F)C5(CCC5)C4)ncc(F)c3n2)c(=O)[nH]1

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.33
KDM4C Q9H3R0 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30727581 0.97 MAPT (0.32) MAPTKDM4C
SCHEMBL30727594 0.90 MAPT (0.32) MAPTKDM4C
SCHEMBL30727565 0.87 MAPT (0.32) MAPTKDM4C
SCHEMBL30727582 0.87 MAPT (0.32) MAPTKDM4C
SCHEMBL30727629 0.84 MAPT (0.34) MAPTKDM4C
SCHEMBL30727587 0.82 MAPT (0.34) MAPTKDM4C
SCHEMBL30727607 0.81 MAPT (0.34) MAPTKDM4C
SCHEMBL30727623 0.80 ATIC (0.33) MAPTKDM4C
SCHEMBL30727593 0.80 MAP3K12 (0.33) MAPTKDM4C
SCHEMBL30727627 0.77 MAPT (0.32) MAPTKDM4C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4532495-A1 CD73 INHIBITOR COMPOUNDS Adorx therapeutics Limited (GB) 2025-04-09 EP claimed
CN-119585273-A CD73 inhibitor compounds 阿道尔克斯治疗有限公司 2025-03-07 CN claimed
WO-2023233130-A1 CD73 INHIBITOR COMPOUNDS AdoRx Therapeutics Limited (GB) 2023-12-07 WO claimed
EP-4532495-A1 CD73 INHIBITOR COMPOUNDS Adorx therapeutics Limited (GB) 2025-04-09 EP disclosed
CN-119585273-A CD73 inhibitor compounds 阿道尔克斯治疗有限公司 2025-03-07 CN disclosed
WO-2023233130-A1 CD73 INHIBITOR COMPOUNDS AdoRx Therapeutics Limited (GB) 2023-12-07 WO disclosed