SCHEMBL30728147

SCHEMBL30728147

CC1(C)CNc2cc(F)cnc21

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
KEAP1 Q14145 3/20 0.33
AKR1B1 P15121 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15108047 1.00 KEAP1 (0.33) KEAP1AKR1B1
SCHEMBL18417744 0.80 CCR1 (0.31)
SCHEMBL15648817 0.79 MEN1 (0.33) AKR1B1
SCHEMBL29713536 0.79 MEN1 (0.33) AKR1B1
SCHEMBL19936144 0.79
SCHEMBL18460890 0.79
SCHEMBL2124329 0.79 HTT (0.34) AKR1B1
SCHEMBL29713514 0.78 XIAP (0.42)
SCHEMBL13732966 0.78 XIAP (0.42)
SCHEMBL13731833 0.77 AR (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117480161-A Novel 2, 3-dihydro-1H-pyrrolo [3,2-b ] pyridine derivatives as sigma ligands 塔拉森调理公司 2024-01-30 CN disclosed