Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.34 |
| ▸ | CHRNG | P07510 | 1/20 | 0.34 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | CHRND | Q07001 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 3/20 | 0.32 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.31 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 5/20 | 0.31 |
| ▸ | CISD1 | Q9NZ45 | 2/20 | 0.31 |
| ▸ | RCOR1 | Q9UKL0 | 2/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25346330 | 0.84 | CHRNA1 (0.40) | ALDH1A1CHRNA1CHRNGCHRNB1CHRNB2 | |
| SCHEMBL31507286 | 0.84 | CHRNA1 (0.40) | ALDH1A1CHRNA1CHRNGCHRNB1CHRNB2 | |
| SCHEMBL29089813 | 0.81 | ALDH1A1 (0.44) | ALDH1A1CHRNA1CHRNGCHRNB1CHRNB2 | |
| SCHEMBL30605856 | 0.81 | ALDH1A1 (0.44) | ALDH1A1CHRNA1CHRNGCHRNB1CHRNB2 | |
| SCHEMBL27070123 | 0.80 | ALDH1A1 (0.40) | ALDH1A1CHRNA1CHRNGCHRNB1CHRNB2 | |
| SCHEMBL29841584 | 0.80 | ALDH1A1 (0.40) | ALDH1A1CHRNA1CHRNGCHRNB1CHRNB2 | |
| SCHEMBL29841593 | 0.78 | ALDH1A1 (0.41) | ALDH1A1CHRNA1CHRNGCHRNB1CHRNB2 | |
| SCHEMBL19357460 | 0.78 | ALDH1A1 (0.41) | ALDH1A1CHRNA1CHRNGCHRNB1CHRNB2 | |
| SCHEMBL28054959 | 0.78 | ALDH1A1 (0.41) | ALDH1A1CHRNA1CHRNGCHRNB1CHRNB2 | |
| SCHEMBL26917303 | 0.78 | ALDH1A1 (0.41) | ALDH1A1CHRNA1CHRNGCHRNB1CHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260028336-A1 | CBL-B INHIBITORS AND METHODS OF USE THEREOF | ARCUS BIOSCIENCES, INC. (US) | 2026-01-29 | — | — | US | disclosed |
| EP-4558501-A1 | CBL-B INHIBITORS AND METHODS OF USE THEREOF | Arcus Biosciences, Inc. (US) | 2025-05-28 | — | — | EP | disclosed |
| WO-2024020034-A1 | CBL-B INHIBITORS AND METHODS OF USE THEREOF | ARCUS BIOSCIENCES, INC. (US) | 2024-01-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260028336-A1 | CBL-B INHIBITORS AND METHODS OF USE THEREOF | CBLB, CBL, CBLC | ALDH1A1 3804/4885CHRNA1 1096/4885CHRNG 1961/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.