Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC10A2 | Q12908 | 18/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26985891 | 1.00 | SLC10A2 (0.41) | SLC10A2KDM4EMEN1LMNAPOLB | |
| SCHEMBL26986042 | 0.96 | SLC10A2 (0.42) | SLC10A2KDM4EMEN1LMNAPOLB | |
| SCHEMBL30728273 | 0.96 | SLC10A2 (0.42) | SLC10A2KDM4EMEN1LMNAPOLB | |
| SCHEMBL5228945 | 0.91 | SLC10A2 (0.42) | SLC10A2 | |
| SCHEMBL27118581 | 0.90 | SLC10A2 (0.43) | SLC10A2 | |
| SCHEMBL26985977 | 0.89 | SLC10A2 (0.40) | SLC10A2 | |
| SCHEMBL30728251 | 0.89 | SLC10A2 (0.40) | SLC10A2 | |
| SCHEMBL22315201 | 0.88 | SLC10A2 (0.41) | SLC10A2 | |
| SCHEMBL30728381 | 0.88 | SLC10A2 (0.39) | SLC10A2 | |
| SCHEMBL26986292 | 0.88 | SLC10A2 (0.39) | SLC10A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4551562-A1 | BENZOTHIA(DI)AZEPINE COMPOUNDS AND THEIR USE AS BILE ACID MODULATORS | Albireo AB (SE) | 2025-05-14 | — | — | EP | disclosed |
| CN-119487013-A | Benzothiepine (di) nitrogen cycloheptatriene compounds Compounds and their use as bile acid modulators | 阿尔比里奥公司 | 2025-02-18 | — | — | CN | disclosed |
| WO-2024008766-A1 | BENZOTHIA(DI)AZEPINE COMPOUNDS AND THEIR USE AS BILE ACID MODULATORS | ALBIREO AB (SE) | 2024-01-11 | — | — | WO | disclosed |