SCHEMBL30728547

SCHEMBL30728547

CCCc1cccc(-c2cccc(F)c2)c1

nearest known ligand 0.52

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 6/20 0.52
ESR2 Q92731 1/20 0.46
CYP17A1 P05093 1/20 0.45
CYP3A4 P08684 1/20 0.45
CYP11B1 P15538 1/20 0.45
CYP11B2 P19099 1/20 0.45
CTSS P25774 1/20 0.44
CTSK P43235 1/20 0.44
DRD2 P14416 1/20 0.42
DRD4 P21917 1/20 0.42
DRD3 P35462 1/20 0.42
AGXT P21549 1/20 0.42
SLC6A3 Q01959 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14041054 1.00 TAAR1 (0.52) TAAR1ESR2CYP17A1CYP3A4CYP11B1
SCHEMBL429765 0.88 TAAR1 (0.63) TAAR1DRD2AGXTSLC6A3
SCHEMBL30777855 0.88 CTSS (0.51) CTSSCTSKDRD2DRD4DRD3
SCHEMBL196298 0.88 CTSS (0.51) CTSSCTSKDRD2DRD4DRD3
SCHEMBL18015823 0.87 AGXT (0.57) TAAR1CTSSCTSKDRD2DRD4
SCHEMBL502700 0.87 TAAR1 (0.69) TAAR1ESR2CYP17A1CYP3A4CYP11B1
Ammonia Solution, Strong SCHEMBL6195952 0.86 TAAR1 (0.61) TAAR1DRD2AGXTSLC6A3
SCHEMBL24005570 0.86 CTSS (0.50) CTSSCTSKAGXT
SCHEMBL3167472 0.84 TAAR1 (0.53) TAAR1ESR2CYP17A1CYP3A4CYP11B1
SCHEMBL9289390 0.84 TAAR1 (0.55) TAAR1ESR2CYP17A1CYP3A4CYP11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116987509-B Liquid crystal compound, composition and application thereof 北京燕化集联光电技术有限公司 2024-09-10 CN disclosed
CN-116987509-A Liquid crystal compound, composition and application thereof 北京燕化集联光电技术有限公司 2023-11-03 CN disclosed