Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 8/20 | 0.73 |
| ▸ | PARP14 | Q460N5 | 6/20 | 0.73 |
| ▸ | PARP15 | Q460N3 | 2/20 | 0.73 |
| ▸ | TNKS | O95271 | 1/20 | 0.73 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.73 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.73 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.64 |
| ▸ | PARP1 | P09874 | 2/20 | 0.57 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.57 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.53 |
| ▸ | FEN1 | P39748 | 1/20 | 0.53 |
| ▸ | F2 | P00734 | 1/20 | 0.52 |
| ▸ | F10 | P00742 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.49 |
| ▸ | TLR4 | O00206 | 1/20 | 0.49 |
| ▸ | TLR2 | O60603 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30434552 | 0.93 | PARP10 (0.83) | PARP10PARP14PARP15TNKSTNKS2 | |
| SCHEMBL2531295 | 0.93 | PARP10 (0.83) | PARP10PARP14PARP15TNKSTNKS2 | |
| Hydrochloric Acid SCHEMBL28772951 | 0.91 | PARP10 (0.80) | PARP10PARP14PARP15TNKSTNKS2 | |
| Methyl Alcohol SCHEMBL8784315 | 0.90 | PARP10 (0.77) | PARP10PARP14PARP15TNKSTNKS2 | |
| SCHEMBL6631040 | 0.84 | PARP10 (1.00) | PARP10PARP14PARP15TNKSTNKS2 | |
| SCHEMBL28313588 | 0.84 | PARP10 (0.73) | PARP10PARP14PARP15TNKSTNKS2 | |
| Diphenylether SCHEMBL3013964 | 0.82 | PARP10 (0.88) | PARP10PARP14PARP15TNKSTNKS2 | |
| SCHEMBL618677 | 0.81 | PARP10 (0.81) | PARP10PARP14PARP15TNKSTNKS2 | |
| SCHEMBL1718819 | 0.80 | PARP10 (0.71) | PARP10PARP14PARP15TNKSTNKS2 | |
| SCHEMBL3650722 | 0.80 | PARP10 (0.78) | PARP10PARP14PARP15TNKSTNKS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117447460-A | Heterocyclic compounds as RIPK1 inhibitors | 南京天印健华医药科技有限公司 | 2024-01-26 | — | — | CN | disclosed |