Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 11/20 | 0.73 |
| ▸ | PARP14 | Q460N5 | 5/20 | 0.73 |
| ▸ | PARP15 | Q460N3 | 3/20 | 0.73 |
| ▸ | TNKS | O95271 | 1/20 | 0.73 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.73 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.73 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.71 |
| ▸ | PARP1 | P09874 | 1/20 | 0.54 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | PARP16 | Q8N5Y8 | 1/20 | 0.50 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.50 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | F2 | P00734 | 3/20 | 0.47 |
| ▸ | F10 | P00742 | 2/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.46 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.46 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL758230 | 0.86 | AKR1C3 (0.72) | PARP10PARP14PARP15TNKSTNKS2 | |
| SCHEMBL8546200 | 0.85 | PARP10 (0.77) | PARP10PARP14PARP15TNKSTNKS2 | |
| SCHEMBL6631040 | 0.85 | PARP10 (1.00) | PARP10PARP14PARP15TNKSTNKS2 | |
| Formic Acid SCHEMBL30728616 | 0.84 | PARP10 (0.73) | PARP10PARP14PARP15TNKSTNKS2 | |
| SCHEMBL2531295 | 0.83 | PARP10 (0.83) | PARP10PARP14PARP15TNKSTNKS2 | |
| SCHEMBL30434552 | 0.83 | PARP10 (0.83) | PARP10PARP14PARP15TNKSTNKS2 | |
| SCHEMBL754740 | 0.83 | PARP10 (1.00) | PARP10PARP14PARP15TNKSTNKS2 | |
| SCHEMBL618677 | 0.82 | PARP10 (0.81) | PARP10PARP14PARP15TNKSTNKS2 | |
| SCHEMBL16880883 | 0.82 | ALDH1A1 (0.58) | PARP10PARP14PARP15TNKSTNKS2 | |
| Hydrochloric Acid SCHEMBL28772951 | 0.82 | PARP10 (0.80) | PARP10PARP14PARP15TNKSTNKS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110234638-A | Heteroaryl phenoxy benzamide KAPPA opiates ligand | 辉瑞大药厂 | 2019-09-13 | — | — | CN | disclosed |