Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NSD2 | O96028 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | APAF1 | O14727 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.42 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | ACHE | P22303 | 6/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16098783 | 1.00 | NSD2 (0.46) | NSD2MAPK1SMN1; SMN2KDM4EAPAF1 | |
| SCHEMBL14219667 | 0.97 | NSD2 (0.45) | NSD2MAPK1SMN1; SMN2KDM4EAPAF1 | |
| SCHEMBL25457780 | 0.97 | NSD2 (0.45) | NSD2MAPK1SMN1; SMN2KDM4EAPAF1 | |
| SCHEMBL14734333 | 0.81 | NPC1 (0.43) | NSD2MAPK1SMN1; SMN2KDM4EAPAF1 | |
| SCHEMBL2406021 | 0.78 | ACHE (0.53) | NSD2MAPK1KDM4EAPAF1ALDH1A1 | |
| SCHEMBL14572401 | 0.74 | ACHE (0.55) | NSD2MAPK1KDM4EAPAF1ALDH1A1 | |
| SCHEMBL565716 | 0.74 | ACHE (0.50) | NSD2MAPK1KDM4EAPAF1ALDH1A1 | |
| SCHEMBL13197744 | 0.72 | KDM4E (0.46) | NSD2MAPK1KDM4EAPAF1ALDH1A1 | |
| SCHEMBL14380308 | 0.72 | KDM4E (0.46) | NSD2MAPK1KDM4EAPAF1ALDH1A1 | |
| SCHEMBL14572400 | 0.70 | ACHE (0.50) | NSD2MAPK1KDM4EAPAF1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4132939-B1 | POLYCYCLIC COMPOUNDS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2024-01-31 | — | — | EP | disclosed |