Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX1 | P51575 | 3/20 | 0.70 |
| ▸ | NPC1 | O15118 | 1/20 | 0.65 |
| ▸ | RAB9A | P51151 | 1/20 | 0.65 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.58 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.55 |
| ▸ | NAMPT | P43490 | 1/20 | 0.55 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | JAK2 | O60674 | 1/20 | 0.51 |
| ▸ | TYK2 | P29597 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL485959 | 0.86 | NPC1 (0.62) | P2RX1NPC1RAB9AKCNK3LMNA | |
| SCHEMBL27070948 | 0.86 | NAMPT (0.56) | P2RX1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL30728722 | 0.86 | NAMPT (0.56) | P2RX1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL485794 | 0.83 | KCNK3 (0.61) | P2RX1NPC1RAB9AKCNK3LMNA | |
| SCHEMBL23447713 | 0.83 | P2RX1 (1.00) | P2RX1NPC1RAB9AKCNK3LMNA | |
| SCHEMBL13736960 | 0.81 | TAS2R14 (0.55) | P2RX1RAB9ALMNAMEN1KMT2A | |
| SCHEMBL4683413 | 0.80 | KCNK3 (0.88) | P2RX1NPC1RAB9AKCNK3LMNA | |
| SCHEMBL11339882 | 0.80 | NPC1 (0.64) | NPC1RAB9AKCNK3BCAT2MEN1 | |
| SCHEMBL2564890 | 0.79 | NPC1 (1.00) | P2RX1NPC1RAB9AKCNK3LMNA | |
| SCHEMBL2480462 | 0.79 | TAS2R14 (0.54) | MEN1KMT2ATAS2R14CYP1A2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4558489-A1 | HETEROARYL DERIVATIVES AS DDRs INHIBITORS | Chiesi Farmaceutici S.p.A. (IT) | 2025-05-28 | — | — | EP | claimed |
| EP-4558490-A1 | HETEROARYL DERIVATIVES AS DDRS INHIBITORS | Chiesi Farmaceutici S.p.A. (IT) | 2025-05-28 | — | — | EP | claimed |
| CN-119585248-A | Heteroaryl derivatives as DDR inhibitors | 奇斯药制品公司 | 2025-03-07 | — | — | CN | claimed |
| CN-119562946-A | Heteroaryl derivatives as DDR inhibitors | 奇斯药制品公司 | 2025-03-04 | — | — | CN | claimed |
| WO-2024017877-A1 | HETEROARYL DERIVATIVES AS DDRs INHIBITORS | CHIESI FARMACEUTICI S.P.A. (IT) | 2024-01-25 | — | — | WO | claimed |
| WO-2024017876-A1 | HETEROARYL DERIVATIVES AS DDRs INHIBITORS | CHIESI FARMACEUTICI S.P.A. (IT) | 2024-01-25 | — | — | WO | claimed |
| EP-4558489-A1 | HETEROARYL DERIVATIVES AS DDRs INHIBITORS | Chiesi Farmaceutici S.p.A. (IT) | 2025-05-28 | — | — | EP | disclosed |
| CN-119585248-A | Heteroaryl derivatives as DDR inhibitors | 奇斯药制品公司 | 2025-03-07 | — | — | CN | disclosed |
| CN-119562946-A | Heteroaryl derivatives as DDR inhibitors | 奇斯药制品公司 | 2025-03-04 | — | — | CN | disclosed |
| WO-2024017876-A1 | HETEROARYL DERIVATIVES AS DDRs INHIBITORS | CHIESI FARMACEUTICI S.P.A. (IT) | 2024-01-25 | — | — | WO | disclosed |