Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.64 |
| ▸ | GLA | P06280 | 2/20 | 0.64 |
| ▸ | GAA | P10253 | 2/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | ORAI1 | Q96D31 | 2/20 | 0.45 |
| ▸ | STIM1 | Q13586 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.44 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.42 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.42 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1329736 | 1.00 | KDM4E (0.64) | KDM4EALDH1A1GLAGAAL3MBTL1 | |
| SCHEMBL29416299 | 0.82 | KDM4E (0.70) | KDM4EALDH1A1GLAGAAL3MBTL1 | |
| SCHEMBL68952 | 0.82 | KDM4E (0.70) | KDM4EALDH1A1GLAGAAL3MBTL1 | |
| SCHEMBL27886976 | 0.82 | KDM4E (0.49) | KDM4EALDH1A1GLAGAAL3MBTL1 | |
| SCHEMBL15454029 | 0.81 | KDM4E (0.42) | KDM4EALDH1A1GLAGAAL3MBTL1 | |
| SCHEMBL17820387 | 0.81 | KDM4E (0.42) | KDM4EALDH1A1GLAGAAL3MBTL1 | |
| SCHEMBL27814741 | 0.81 | ALDH1A1 (0.43) | KDM4EALDH1A1GLAGAAL3MBTL1 | |
| SCHEMBL3290788 | 0.81 | TSHR (0.50) | KDM4EALDH1A1GLAGAAKMT2A | |
| SCHEMBL28904581 | 0.80 | KMT2A (0.46) | KDM4EALDH1A1GLAGAAL3MBTL1 | |
| SCHEMBL9107394 | 0.79 | KDM4E (0.66) | KDM4EALDH1A1GLAGAAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4558489-A1 | HETEROARYL DERIVATIVES AS DDRs INHIBITORS | Chiesi Farmaceutici S.p.A. (IT) | 2025-05-28 | — | — | EP | disclosed |
| WO-2024017876-A1 | HETEROARYL DERIVATIVES AS DDRs INHIBITORS | CHIESI FARMACEUTICI S.P.A. (IT) | 2024-01-25 | — | — | WO | disclosed |