Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | TPH1 | P17752 | 1/20 | 0.33 |
| ▸ | ADK | P55263 | 1/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.33 |
| ▸ | AKT1 | P31749 | 1/20 | 0.33 |
| ▸ | AKT2 | P31751 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30223679 | 0.87 | SIGMAR1 (0.34) | SIGMAR1TPH1 | |
| SCHEMBL13286173 | 0.86 | SIGMAR1 (0.46) | SIGMAR1PRMT5SCN9ATPH1PIK3CG | |
| SCHEMBL21201777 | 0.80 | SIGMAR1 (0.39) | SIGMAR1PRMT5SCN9ATPH1 | |
| SCHEMBL10247590 | 0.80 | SIGMAR1 (0.39) | SIGMAR1PRMT5SCN9ATPH1PIK3CG | |
| SCHEMBL24902073 | 0.79 | SIGMAR1 (0.39) | SIGMAR1PRMT5SCN9ATPH1P2RX7 | |
| SCHEMBL30749810 | 0.79 | SIGMAR1 (0.39) | SIGMAR1PRMT5SCN9ATPH1P2RX7 | |
| SCHEMBL871452 | 0.79 | SIGMAR1 (0.39) | SIGMAR1PRMT5SCN9ATPH1P2RX7 | |
| SCHEMBL13058244 | 0.79 | SIGMAR1 (0.48) | SIGMAR1PRMT5PIK3CGAKT1AKT2 | |
| SCHEMBL10222870 | 0.79 | SIGMAR1 (0.45) | SIGMAR1PRMT5PIK3CGAKT1AKT2 | |
| SCHEMBL13243498 | 0.79 | SIGMAR1 (0.45) | SIGMAR1PRMT5PIK3CGAKT1AKT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117451899-A | Method for detecting impurities in crude drug of amino acid protein kinase inhibitor | 淄博高新技术产业开发区生物医药研究院 | 2024-01-26 | — | — | CN | claimed |
| CN-117451899-A | Method for detecting impurities in crude drug of amino acid protein kinase inhibitor | 淄博高新技术产业开发区生物医药研究院 | 2024-01-26 | — | — | CN | disclosed |
| CN-117451899-A | Method for detecting impurities in crude drug of amino acid protein kinase inhibitor | 淄博高新技术产业开发区生物医药研究院 | 2024-01-26 | — | — | CN | disclosed |