Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 17/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3417113 | 0.86 | REN (0.41) | RENCYP3A4PDE4B | |
| SCHEMBL3080328 | 0.80 | REN (0.43) | RENCYP3A4 | |
| SCHEMBL3259291 | 0.76 | REN (0.52) | RENCYP3A4PDE4B | |
| SCHEMBL3072934 | 0.76 | REN (0.42) | RENCYP3A4 | |
| SCHEMBL3072786 | 0.76 | REN (0.42) | REN | |
| SCHEMBL3263399 | 0.75 | REN (0.38) | RENCYP3A4PDE4B | |
| SCHEMBL5561759 | 0.72 | REN (0.53) | RENCYP3A4 | |
| SCHEMBL3416611 | 0.72 | REN (0.43) | RENCYP3A4 | |
| SCHEMBL7509751 | 0.72 | REN (0.38) | REN | |
| SCHEMBL3076941 | 0.70 | REN (0.39) | RENCYP3A4PDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7790715-B2 | Organic compounds | NOVARTIS AG (CH) | 2010-09-07 | — | — | US | disclosed |