Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27113257 | 0.83 | MAPT (0.61) | MAPTALDH1A1MAPK1LMNAMEN1 | |
| SCHEMBL4714774 | 0.83 | MAPT (0.58) | MAPTALDH1A1MAPK1LMNAMEN1 | |
| SCHEMBL19221763 | 0.81 | MAPT (0.56) | MAPTALDH1A1MAPK1LMNAMEN1 | |
| SCHEMBL30729399 | 0.81 | MAPT (0.42) | MAPTALDH1A1MAPK1LMNAMEN1 | |
| SCHEMBL520304 | 0.78 | LMNA (0.60) | MAPTALDH1A1MAPK1LMNAMEN1 | |
| SCHEMBL19221765 | 0.78 | MAPT (0.53) | MAPTALDH1A1MAPK1LMNAMEN1 | |
| SCHEMBL9983992 | 0.76 | MAPT (0.61) | MAPTALDH1A1MAPK1LMNAMEN1 | |
| SCHEMBL2018527 | 0.76 | MAPT (0.61) | MAPTALDH1A1MAPK1LMNAMEN1 | |
| SCHEMBL16651521 | 0.76 | MAPT (0.61) | MAPTALDH1A1MAPK1LMNAMEN1 | |
| SCHEMBL6610334 | 0.76 | MAPT (0.61) | MAPTALDH1A1MAPK1LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117377673-A | HPK1 antagonists and uses thereof | 林伯士萨顿公司 | 2024-01-09 | — | — | CN | disclosed |