SCHEMBL30729665

SCHEMBL30729665

CC(C)C[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](C)N)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)O

nearest known ligand 0.53

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 1/20 0.53
NPY1R P25929 1/20 0.52
NPY2R P49146 1/20 0.52
NPY4R P50391 1/20 0.52
ACE P12821 5/20 0.48
IL1RN P18510 3/20 0.47
ERAP2 Q6P179 3/20 0.47
ERAP1 Q9NZ08 1/20 0.45
OPRM1 P35372 1/20 0.45
OPRD1 P41143 1/20 0.45
MME P08473 1/20 0.44
CPA1 P15085 1/20 0.44
ACE2 Q9BYF1 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30729668 1.00 FOLH1 (0.53) FOLH1NPY1RNPY2RNPY4RACE
SCHEMBL29615620 0.95 ACE (0.48) FOLH1NPY1RNPY2RNPY4RACE
SCHEMBL29626745 0.91 MME (0.45) FOLH1NPY1RNPY2RNPY4RACE
SCHEMBL29630559 0.91 ERAP2 (0.41) NPY1RNPY2RNPY4RIL1RNERAP2
SCHEMBL30034864 0.91 NPY1R (0.53) FOLH1NPY1RNPY2RNPY4RACE
SCHEMBL29705780 0.91 OPRD1 (0.54) FOLH1NPY1RNPY2RNPY4RACE
SCHEMBL30400489 0.91 NPY4R (0.52) FOLH1NPY1RNPY2RNPY4ROPRM1
SCHEMBL29993760 0.90 NPY4R (0.53) FOLH1NPY1RNPY2RNPY4RACE
SCHEMBL29815237 0.88 NPY4R (0.51) FOLH1NPY1RNPY2RNPY4ROPRM1
SCHEMBL29531471 0.87 ACE (0.47) FOLH1NPY1RNPY2RNPY4RACE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117624291-A Uric acid-reducing tetrapeptide with hypoxanthine binding capacity, and encoding gene and application thereof 华南理工大学 2024-03-01 CN disclosed
CN-117624291-A Uric acid-reducing tetrapeptide with hypoxanthine binding capacity, and encoding gene and application thereof 华南理工大学 2024-03-01 CN disclosed