Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLS | O94925 | 1/20 | 0.57 |
| ▸ | IDO1 | P14902 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.48 |
| ▸ | PPARG | P37231 | 2/20 | 0.48 |
| ▸ | EGFR | P00533 | 7/20 | 0.46 |
| ▸ | ERBB2 | P04626 | 7/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL217553 | 1.00 | GLS (0.57) | GLSIDO1MEN1KMT2AEPHX2 | |
| SCHEMBL5435879 | 0.86 | GLS (0.61) | GLSKMT2ACYP1A2CYP2D6CYP2C19 | |
| SCHEMBL1728790 | 0.86 | GLS (0.64) | GLSMAPTCNR1ACHECNR2 | |
| SCHEMBL11002083 | 0.83 | GLS (0.67) | GLSMEN1KMT2AMAPTADORA2A | |
| SCHEMBL3506368 | 0.83 | GLS (0.54) | GLSADORA2AADORA1RECQL | |
| SCHEMBL3376313 | 0.83 | GLS (0.54) | GLSMEN1KMT2AEPHX2PPARG | |
| SCHEMBL29377015 | 0.82 | GLS (0.58) | GLSEGFRERBB2GRIN1GRIN2B | |
| SCHEMBL27083759 | 0.82 | GLS (0.58) | GLSEGFRERBB2GRIN1GRIN2B | |
| SCHEMBL16213110 | 0.81 | ERBB2 (0.61) | MEN1KMT2AEGFRERBB2CYP1A2 | |
| SCHEMBL3378095 | 0.81 | GLS (0.57) | GLSGRIN1GRIN2BMAPTCNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024026056-A2 | HETEROARYL COMPOUNDS AS EGFR INHIBITORS AND THEIR USES | ACCUTAR BIOTECHNOLOGY, INC. (US) | 2024-02-01 | — | — | WO | disclosed |