Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERBB2 | P04626 | 20/20 | 0.46 |
| ▸ | EGFR | P00533 | 14/20 | 0.44 |
| ▸ | LCK | P06239 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30729944 | 1.00 | ERBB2 (0.46) | ERBB2EGFRLCKKCNH2 | |
| SCHEMBL27096985 | 1.00 | ERBB2 (0.46) | ERBB2EGFRLCKKCNH2 | |
| SCHEMBL27097008 | 0.92 | ERBB2 (0.47) | ERBB2EGFRLCKKCNH2 | |
| SCHEMBL27138279 | 0.92 | ERBB2 (0.47) | ERBB2EGFRLCKKCNH2 | |
| SCHEMBL27311335 | 0.92 | ERBB2 (0.43) | ERBB2EGFRLCKKCNH2 | |
| SCHEMBL27096904 | 0.83 | ERBB2 (0.41) | ERBB2EGFRKCNH2 | |
| SCHEMBL27096809 | 0.78 | GPR119 (0.37) | — | |
| SCHEMBL27096997 | 0.78 | ERBB2 (0.43) | ERBB2EGFRKCNH2 | |
| SCHEMBL27138432 | 0.78 | ERBB2 (0.39) | ERBB2EGFRKCNH2 | |
| SCHEMBL30729854 | 0.71 | ERBB2 (0.59) | ERBB2EGFRKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024026056-A2 | HETEROARYL COMPOUNDS AS EGFR INHIBITORS AND THEIR USES | ACCUTAR BIOTECHNOLOGY, INC. (US) | 2024-02-01 | — | — | WO | disclosed |