Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 18/20 | 0.53 |
| ▸ | ERBB2 | P04626 | 18/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.47 |
| ▸ | PRKCG | P05129 | 1/20 | 0.47 |
| ▸ | PRKCB | P05771 | 1/20 | 0.47 |
| ▸ | LCK | P06239 | 1/20 | 0.47 |
| ▸ | CDK1 | P06493 | 1/20 | 0.47 |
| ▸ | MET | P08581 | 1/20 | 0.47 |
| ▸ | PRKCA | P17252 | 1/20 | 0.47 |
| ▸ | PRKCH | P24723 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.47 |
| ▸ | PRKCI | P41743 | 1/20 | 0.47 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.47 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.47 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.47 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.47 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL215702 | 1.00 | EGFR (0.53) | EGFRERBB2EPHX2PPARGRECQL | |
| Hydrochloric Acid SCHEMBL1353996 | 0.99 | EGFR (0.52) | EGFRERBB2EPHX2PPARGPRKD3 | |
| SCHEMBL1015246 | 0.89 | RECQL (0.47) | EGFRERBB2EPHX2PPARGRECQL | |
| SCHEMBL3321902 | 0.87 | HTR2A (0.49) | EGFRERBB2EPHX2PPARGRECQL | |
| SCHEMBL3319948 | 0.85 | ERBB2 (0.50) | EGFRERBB2RECQLMET | |
| SCHEMBL29992643 | 0.84 | RECQL (0.66) | EGFRERBB2RECQL | |
| SCHEMBL870390 | 0.84 | RECQL (0.66) | EGFRERBB2RECQL | |
| SCHEMBL21057948 | 0.84 | EGFR (0.53) | EGFRERBB2EPHX2PPARGRECQL | |
| SCHEMBL21058074 | 0.84 | EGFR (0.50) | EGFRERBB2EPHX2PPARGRECQL | |
| SCHEMBL11949602 | 0.84 | EGFR (0.58) | EGFRERBB2EPHX2PPARGRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024026056-A2 | HETEROARYL COMPOUNDS AS EGFR INHIBITORS AND THEIR USES | ACCUTAR BIOTECHNOLOGY, INC. (US) | 2024-02-01 | — | — | WO | disclosed |