Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1F | P30939 | 18/20 | 0.85 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.85 |
| ▸ | DRD5 | P21918 | 1/20 | 0.85 |
| ▸ | HTR1D | P28221 | 1/20 | 0.85 |
| ▸ | HTR1E | P28566 | 1/20 | 0.85 |
| ▸ | HTR7 | P34969 | 1/20 | 0.85 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.85 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.85 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.85 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | HTR1A | P08908 | 1/20 | 0.56 |
| ▸ | HTR1B | P28222 | 1/20 | 0.56 |
| ▸ | HTR2A | P28223 | 1/20 | 0.56 |
| ▸ | HTR2C | P28335 | 1/20 | 0.56 |
| ▸ | HTR2B | P41595 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2537137 | 1.00 | HTR1F (0.85) | HTR1FCHRM5DRD5HTR1DHTR1E | |
| SCHEMBL30909086 | 0.93 | HTR1F (0.76) | HTR1FCHRM5DRD5HTR1DHTR1E | |
| SCHEMBL2538050 | 0.93 | HTR1F (0.76) | HTR1FCHRM5DRD5HTR1DHTR1E | |
| Hydrochloric Acid SCHEMBL2531448 | 0.92 | HTR1F (0.74) | HTR1FCHRM5DRD5HTR1DHTR1E | |
| Lasmiditan SCHEMBL29376817 | 0.92 | HTR1F (1.00) | HTR1FCHRM5DRD5HTR1DHTR1E | |
| Lasmiditan SCHEMBL536057 | 0.92 | HTR1F (1.00) | HTR1FCHRM5DRD5HTR1DHTR1E | |
| Lasmiditan SCHEMBL2536468 | 0.91 | HTR1F (0.98) | HTR1FCHRM5DRD5HTR1DHTR1E | |
| Lasmiditan SCHEMBL29598155 | 0.91 | HTR1F (0.98) | HTR1FCHRM5DRD5HTR1DHTR1E | |
| SCHEMBL30909284 | 0.91 | HTR1F (0.71) | HTR1FCHRM5DRD5HTR1DHTR1E | |
| SCHEMBL2537040 | 0.91 | HTR1F (0.71) | HTR1FCHRM5DRD5HTR1DHTR1E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117630235-A | HPLC analysis and detection method for lamiditan hemisuccinate and related substances thereof | 江苏万邦生化医药集团有限责任公司 | 2024-03-01 | — | — | CN | claimed |
| WO-2024073845-A1 | METHODS AND PHARMACOLOGICAL AGENTS FOR INCREASING EXPANSION, ENGRAFTMENT OR IMMUNE OUTPUT OF HUMAN HEMATOPOIETIC STEM CELLS IN TRANSPLANTATION AND DISEASE SETTINGS | VALORISATION HSJ, LIMITED PARTNERSHIP (CA) | 2024-04-11 | — | — | WO | disclosed |
| CN-117630235-A | HPLC analysis and detection method for lamiditan hemisuccinate and related substances thereof | 江苏万邦生化医药集团有限责任公司 | 2024-03-01 | — | — | CN | disclosed |