SCHEMBL30730367

SCHEMBL30730367

COC(=O)C(C)n1ccc(C2CCCC2)n1

nearest known ligand 0.37

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TACR3 P29371 1/20 0.37
MGLL Q99685 1/20 0.36
CNR2 P34972 2/20 0.35
PSMB8 P28062 1/20 0.35
PSMB9 P28065 1/20 0.35
PSMB5 P28074 1/20 0.35
KCNJ6 P48051 1/20 0.35
KCNJ5 P48544 1/20 0.35
KCNJ3 P48549 1/20 0.35
P2RX3 P56373 2/20 0.34
SLC6A3 Q01959 3/20 0.34
ALDH1A1 P00352 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
TSHR P16473 1/20 0.34
ACACB O00763 1/20 0.34
CAPN1 P07384 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30730269 0.84 KDM4E (0.35) MGLLPSMB8PSMB9PSMB5KCNJ6
SCHEMBL11826416 0.80 PSMB8 (0.37) MGLLCNR2PSMB8PSMB9PSMB5
SCHEMBL23163078 0.78 NPC1 (0.38) MGLLALDH1A1CAPN1
SCHEMBL21462908 0.78 NPC1 (0.38) MGLLALDH1A1CAPN1
SCHEMBL29760265 0.78 NPC1 (0.38) MGLLALDH1A1CAPN1
SCHEMBL27396462 0.77 NPC1 (0.38) MGLLPSMB8PSMB9PSMB5ALDH1A1
SCHEMBL16434653 0.76 CYP19A1 (0.39) PSMB8PSMB9PSMB5ALDH1A1
SCHEMBL24117825 0.74 NPC1 (0.38) MGLLALDH1A1
SCHEMBL30730193 0.73 ALDH1A1 (0.34) ALDH1A1
SCHEMBL12719014 0.71 CYP19A1 (0.40) CNR2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4562015-A2 CDK2 INHIBITORS AND METHODS OF USING THE SAME Cedilla Therapeutics, Inc. (US) 2025-06-04 EP disclosed
WO-2024026481-A2 CDK2 INHIBITORS AND METHODS OF USING THE SAME CEDILLA THERAPEUTICS, INC. (US) 2024-02-01 WO disclosed