Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 1/20 | 0.60 |
| ▸ | CALCRL | Q16602 | 1/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.49 |
| ▸ | PTGES | O14684 | 2/20 | 0.49 |
| ▸ | MAOB | P27338 | 2/20 | 0.49 |
| ▸ | LCK | P06239 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.46 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29149118 | 1.00 | ERN1 (0.60) | ERN1CALCRLALOX5PTGESMAOB | |
| SCHEMBL11672123 | 0.86 | CALCRL (0.67) | ERN1CALCRLALOX5PTGESMAOB | |
| SCHEMBL11672469 | 0.83 | ABCB1 (0.65) | ERN1ALOX5PTGESMAOBMAOA | |
| SCHEMBL29149075 | 0.82 | ERN1 (0.57) | ERN1CALCRLALOX5PTGESMAOB | |
| SCHEMBL30730422 | 0.82 | ERN1 (0.57) | ERN1CALCRLALOX5PTGESMAOB | |
| SCHEMBL12994030 | 0.80 | CYP1A1 (0.48) | ERN1MAOBMAOACYP1A1CYP1B1 | |
| SCHEMBL30730521 | 0.80 | ERN1 (0.55) | ERN1CALCRLALOX5PTGESMAOB | |
| SCHEMBL18717295 | 0.80 | ERN1 (0.69) | ERN1CALCRLALOX5PTGESMAOB | |
| SCHEMBL29149117 | 0.80 | ERN1 (0.55) | ERN1CALCRLALOX5PTGESMAOB | |
| SCHEMBL28792949 | 0.79 | CASP3 (0.63) | ERN1ALOX5MAOBMAOAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122029153-A | Aromatic hydrocarbon receptor modulator compound, and preparation method and application thereof | 德明药泰生物技术（深圳）有限公司 | 2026-05-12 | — | — | CN | disclosed |
| WO-2025082312-A1 | AROMATIC HYDROCARBON RECEPTOR MODULATOR COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 德明药泰生物技术（深圳）有限公司 | 2025-04-24 | — | — | WO | disclosed |
| CN-117447402-A | Aromatic hydrocarbon receptor modulator compound, and preparation method and application thereof | 德明药泰生物技术（深圳）有限公司 | 2024-01-26 | — | — | CN | disclosed |