Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 2/20 | 0.41 |
| ▸ | PIP4K2A | P48426 | 2/20 | 0.39 |
| ▸ | PIM1 | P11309 | 3/20 | 0.36 |
| ▸ | HPGDS | O60760 | 1/20 | 0.36 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.35 |
| ▸ | ACVR1 | Q04771 | 2/20 | 0.35 |
| ▸ | FEN1 | P39748 | 1/20 | 0.35 |
| ▸ | PIP4K2C | Q8TBX8 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CD38 | P28907 | 1/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22553917 | 1.00 | ALOX5AP (0.41) | ALOX5APPIP4K2APIM1HPGDSTGFBR1 | |
| SCHEMBL22553859 | 0.80 | PIP4K2A (0.45) | ALOX5APPIP4K2APIM1HPGDSPIP4K2C | |
| SCHEMBL22553813 | 0.77 | CNR2 (0.38) | ALOX5APPIP4K2AHPGDSTGFBR1ACVR1 | |
| SCHEMBL30730848 | 0.77 | CNR2 (0.38) | ALOX5APPIP4K2AHPGDSTGFBR1ACVR1 | |
| SCHEMBL22554275 | 0.74 | NPC1 (0.44) | ALOX5APHPGDSFEN1GAAAKR1C3 | |
| SCHEMBL30731090 | 0.74 | NPC1 (0.44) | ALOX5APHPGDSFEN1GAAAKR1C3 | |
| SCHEMBL30731017 | 0.74 | NPC1 (0.44) | ALOX5APHPGDSFEN1GAAAKR1C3 | |
| SCHEMBL22554214 | 0.73 | CDK8 (0.38) | ALOX5APPIM1HPGDSACVR1FEN1 | |
| SCHEMBL30730798 | 0.73 | CDK8 (0.38) | ALOX5APPIM1HPGDSACVR1FEN1 | |
| SCHEMBL22553739 | 0.72 | JAK2 (0.43) | PIM1CNR2PIM3PIM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112088157-B | Aryl-bipyridylamine derivatives as phosphatidylinositol phosphokinase inhibitors | 拉文纳制药公司 | 2023-12-26 | — | — | CN | claimed |
| CN-112088157-B | Aryl-bipyridylamine derivatives as phosphatidylinositol phosphokinase inhibitors | 拉文纳制药公司 | 2023-12-26 | — | — | CN | disclosed |