Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIP4K2A | P48426 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.38 |
| ▸ | F10 | P00742 | 2/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.37 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.37 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.37 |
| ▸ | SYK | P43405 | 6/20 | 0.36 |
| ▸ | CCNC | P24863 | 2/20 | 0.36 |
| ▸ | CDK8 | P49336 | 2/20 | 0.36 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.35 |
| ▸ | FYN | P06241 | 1/20 | 0.35 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.34 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.34 |
| ▸ | BMPR1A | P36894 | 1/20 | 0.34 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.34 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.34 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.33 |
| ▸ | PHGDH | O43175 | 1/20 | 0.33 |
| ▸ | KIT | P10721 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22554263 | 1.00 | PIP4K2A (0.41) | PIP4K2ABRD4BRDTF10PRSS1 | |
| SCHEMBL22553767 | 0.89 | BRD4 (0.46) | PIP4K2ABRD4BRDTF10PRSS1 | |
| SCHEMBL30730859 | 0.89 | BRD4 (0.46) | PIP4K2ABRD4BRDTF10PRSS1 | |
| SCHEMBL22553845 | 0.84 | AXL (0.42) | PIP4K2A | |
| SCHEMBL22554116 | 0.76 | BRD4 (0.39) | PIP4K2ABRD4BRDTF10PRSS1 | |
| SCHEMBL22553979 | 0.75 | BRD4 (0.48) | PIP4K2ABRD4BRDTF10PRSS1 | |
| SCHEMBL22553977 | 0.75 | PIP4K2A (0.40) | PIP4K2ABRD4BRDTF10PRSS1 | |
| SCHEMBL22554034 | 0.73 | BRD4 (0.44) | PIP4K2ABRD4BRDTF10PRSS1 | |
| SCHEMBL22553737 | 0.73 | BRD4 (0.48) | PIP4K2ABRD4BRDTF10PRSS1 | |
| SCHEMBL22554262 | 0.71 | CCNC (0.39) | BRD4BRDTF10PRSS1PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112088157-B | Aryl-bipyridylamine derivatives as phosphatidylinositol phosphokinase inhibitors | 拉文纳制药公司 | 2023-12-26 | — | — | CN | claimed |
| CN-112088157-B | Aryl-bipyridylamine derivatives as phosphatidylinositol phosphokinase inhibitors | 拉文纳制药公司 | 2023-12-26 | — | — | CN | disclosed |