Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.46 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.46 |
| ▸ | PIP4K2A | P48426 | 1/20 | 0.45 |
| ▸ | SYK | P43405 | 6/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.38 |
| ▸ | FYN | P06241 | 1/20 | 0.38 |
| ▸ | CCNC | P24863 | 3/20 | 0.38 |
| ▸ | CDK8 | P49336 | 3/20 | 0.38 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.37 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.37 |
| ▸ | F10 | P00742 | 1/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.37 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.37 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22553767 | 1.00 | BRD4 (0.46) | BRD4BRDTPIP4K2ASYKMAP4K4 | |
| SCHEMBL22554263 | 0.89 | PIP4K2A (0.41) | BRD4BRDTPIP4K2ASYKMAP4K4 | |
| SCHEMBL30730829 | 0.89 | PIP4K2A (0.41) | BRD4BRDTPIP4K2ASYKMAP4K4 | |
| SCHEMBL22553979 | 0.86 | BRD4 (0.48) | BRD4BRDTPIP4K2ASYKCCNC | |
| SCHEMBL22553845 | 0.85 | AXL (0.42) | PIP4K2A | |
| SCHEMBL22554034 | 0.82 | BRD4 (0.44) | BRD4BRDTPIP4K2ASYKMAP4K4 | |
| SCHEMBL22553737 | 0.81 | BRD4 (0.48) | BRD4BRDTPIP4K2ASYKMAP4K4 | |
| SCHEMBL22554116 | 0.79 | BRD4 (0.39) | BRD4BRDTPIP4K2ASYKMAP4K4 | |
| SCHEMBL22553977 | 0.74 | PIP4K2A (0.40) | BRD4BRDTPIP4K2ASYKCCNC | |
| SCHEMBL22553850 | 0.73 | CHEK2 (0.54) | MAP4K4FYNTGFBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112088157-B | Aryl-bipyridylamine derivatives as phosphatidylinositol phosphokinase inhibitors | 拉文纳制药公司 | 2023-12-26 | — | — | CN | claimed |
| CN-112088157-B | Aryl-bipyridylamine derivatives as phosphatidylinositol phosphokinase inhibitors | 拉文纳制药公司 | 2023-12-26 | — | — | CN | disclosed |